Unusual bleeding or discharge. Blood in the vaginal discharge or bleeding after intercourse.

A lump in the breast or elsewhere.

A sore that does not heal.

Changes in bowel or bladder habits.

Hoarseness or cough.

Indigestion or difficulty in swallowing.

Change in the size of a birthmark or mole.

A weight loss, especially in someone who eats well.

A low persistent fever could be an indication of leukaemia or Hodgkin's disease.

Persistent itching and skin rashes.

Persistent pain and soft swelling of the bones and surrounding tissues.

Any sore in the mouth that doesn't heal after usual treatment, could point to oral cancer.